Ipamorelin & CJC-1295 Dosage Guide
Reconstitution math, syringe draw reference, and the CJC-1295 + ipamorelin stack protocol — everything in one place.
What Are Ipamorelin and CJC-1295?
Two Compounds, One Common Stack
Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. It has been investigated in preclinical and early clinical research for its potential to stimulate growth hormone release with a favorable selectivity profile compared to earlier GHRP compounds.
CJC-1295 (also called Modified GRF 1-29 or Mod GRF 1-29 when without the DAC modification) is a growth hormone releasing hormone (GHRH) analogue. It has been studied for its potential to extend the half-life of endogenous GHRH signaling, promoting pulsatile growth hormone release.
The two compounds are almost universally discussed and used together in the research community. Ipamorelin acts on the ghrelin receptor while CJC-1295 acts on the GHRH receptor — the combination is proposed to work through complementary mechanisms to amplify GH pulse amplitude.
Important: CJC-1295 with DAC and CJC-1295 without DAC (Mod GRF 1-29) are different compounds with different half-lives and dosing frequencies. This guide covers CJC-1295 without DAC, which is the more commonly used form in research protocols.
Dosing Reference
Common Research Doses
| Compound | Common dose | Frequency | Timing |
|---|---|---|---|
| Ipamorelin | 200–300 mcg | Once to three times daily | Fasted, preferably before sleep |
| CJC-1295 (no DAC) | 100–300 mcg | Same injection as ipamorelin | Always paired with ipamorelin |
Both compounds are dosed in micrograms (mcg). To use the calculator, convert to mg: 200 mcg = 0.20 mg, 300 mcg = 0.30 mg.
Most research protocols administer ipamorelin and CJC-1295 together in the same injection. The most common timing is before sleep in a fasted state, as GH secretion naturally peaks during sleep and fasting may enhance the GH response.
Reconstitution Reference
How Much BAC Water to Add
Ipamorelin and CJC-1295 are each supplied as separate lyophilized vials and reconstituted separately. Reconstitute each vial individually before drawing into the same syringe for injection.
Ipamorelin
| Vial size | BAC water | Concentration | Doses at 200 mcg | Doses at 300 mcg |
|---|---|---|---|---|
| 2 mg | 2.0 mL | 1.0 mg/mL | 10 | 6 |
| 5 mg | 2.0 mL | 2.5 mg/mL | 25 | 16 |
| 5 mg | 5.0 mL | 1.0 mg/mL | 25 | 16 |
CJC-1295 (no DAC)
| Vial size | BAC water | Concentration | Doses at 100 mcg | Doses at 300 mcg |
|---|---|---|---|---|
| 2 mg | 2.0 mL | 1.0 mg/mL | 20 | 6 |
| 5 mg | 2.0 mL | 2.5 mg/mL | 50 | 16 |
| 5 mg | 5.0 mL | 1.0 mg/mL | 50 | 16 |
Calculate your exact syringe draw for each compound
Open the Calculator →Syringe Draw Reference
Ipamorelin Draw Reference
| Dose | Draw to |
|---|---|
| 100 mcg (0.10 mg) | 10 units |
| 200 mcg (0.20 mg) | 20 units |
| 300 mcg (0.30 mg) | 30 units |
| Dose | Draw to |
|---|---|
| 100 mcg (0.10 mg) | 4 units |
| 200 mcg (0.20 mg) | 8 units |
| 300 mcg (0.30 mg) | 12 units |
CJC-1295 Draw Reference
| Dose | Draw to |
|---|---|
| 100 mcg (0.10 mg) | 10 units |
| 200 mcg (0.20 mg) | 20 units |
| 300 mcg (0.30 mg) | 30 units |
| Dose | Draw to |
|---|---|
| 100 mcg (0.10 mg) | 4 units |
| 200 mcg (0.20 mg) | 8 units |
| 300 mcg (0.30 mg) | 12 units |
To combine in one syringe: draw ipamorelin first, then draw CJC-1295 into the same syringe. Calculate each volume separately using the calculator before combining.
The Stack Protocol
Ipamorelin + CJC-1295 Combined Protocol
The most common research protocol combines both compounds in a single subcutaneous injection once daily, typically before sleep in a fasted state. Some protocols use two or three injections daily — morning fasted and before sleep are the most common timing points.
| Protocol | Ipamorelin dose | CJC-1295 dose | Frequency | Timing |
|---|---|---|---|---|
| Standard | 200 mcg | 200 mcg | Once daily | Before sleep, fasted |
| Higher range | 300 mcg | 300 mcg | Once daily | Before sleep, fasted |
| Twice daily | 200 mcg | 200 mcg | Twice daily | Morning fasted + before sleep |
Fasted administration is preferred based on the hypothesis that insulin blunts GH release. Wait at least 2 hours after eating before injecting. Most researchers do not eat for 30–60 minutes after injection.
Supplies Required
| Item | Spec | Notes |
|---|---|---|
| Ipamorelin vial | Lyophilized powder | Store at -20°C until use |
| CJC-1295 (no DAC) vial | Lyophilized powder | Store at -20°C until use |
| Bacteriostatic water | USP, 0.9% benzyl alcohol | One vial per peptide or shared |
| Insulin syringes | U-100, 31g, 0.3 mL | Smaller syringe preferred for low mcg doses |
| Alcohol prep pads | 70% isopropyl, sterile | One per vial entry, one per site |
| Sharps container | Puncture-resistant | Required |
Sourcing
Recommended Research Supplier
PSPeptides carries third-party tested, research-grade ipamorelin and CJC-1295 with published COAs.
Discount Code: BANANAS10
Website: pspeptides.com/?ref=bananas
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