BPC-157 Dosage & Protocol Guide
Subcutaneous vs oral dosing, reconstitution math, syringe draw reference, and the BPC-157 + TB-500 stack — everything in one place.
What Is BPC-157?
BPC-157 (Body Protection Compound 157) is a synthetic pentadecapeptide composed of 15 amino acids, derived from a partial sequence of a protein found in human gastric juice. It has been investigated in preclinical research for potential effects related to angiogenesis, tissue repair processes, and the gastrointestinal tract. BPC-157 is not approved by the FDA for human use and is classified as a research chemical.
BPC-157 Dosing Protocols
Subcutaneous vs Oral
Most BPC-157 research protocols use subcutaneous injection, typically administered near the area of interest. Oral administration is also used in protocols targeting the gastrointestinal tract, since BPC-157 is derived from a protein found in gastric juice and is reported to be acid-stable.
| Protocol type | Dose range | Frequency | Duration |
|---|---|---|---|
| Low range (subQ) | 200–250 mcg | Once daily | 4–6 weeks |
| Standard (subQ) | 250–500 mcg | Once or twice daily | 4–8 weeks |
| Higher range (subQ) | 500–750 mcg | Twice daily | 4–8 weeks |
| Oral (GI-focused) | 250–500 mcg | Once or twice daily | Variable duration |
BPC-157 is dosed in micrograms (mcg), not milligrams. This distinguishes it from TB-500 which is dosed in mg. Always confirm your units before calculating — a 1000× error is easy to make.
Reconstitution Reference
How Much BAC Water to Add
| Vial size | BAC water | Concentration | Doses at 250 mcg | Doses at 500 mcg |
|---|---|---|---|---|
| 5 mg | 2.0 mL | 2.5 mg/mL (2500 mcg/mL) | 20 (250 mcg) | 10 (500 mcg) |
| 5 mg | 5.0 mL | 1.0 mg/mL (1000 mcg/mL) | 20 (250 mcg) | 10 (500 mcg) |
| 10 mg | 2.0 mL | 5.0 mg/mL (5000 mcg/mL) | 40 (250 mcg) | 20 (500 mcg) |
| 10 mg | 5.0 mL | 2.0 mg/mL (2000 mcg/mL) | 40 (250 mcg) | 20 (500 mcg) |
Calculate your exact syringe draw
Open the Calculator →Syringe Draw Reference
| Dose | Draw to |
|---|---|
| 100 mcg | 4 units |
| 200 mcg | 8 units |
| 250 mcg | 10 units |
| 500 mcg | 20 units |
| 750 mcg | 30 units |
| Dose | Draw to |
|---|---|
| 100 mcg | 10 units |
| 200 mcg | 20 units |
| 250 mcg | 25 units |
| 500 mcg | 50 units |
| 750 mcg | 75 units |
Units refer to insulin syringe units (100 units = 1 mL). Use the calculator for any reconstitution ratio not shown here.
BPC-157 + TB-500 Stack
The Most Common BPC-157 Stack
BPC-157 and TB-500 are frequently used together in research protocols. BPC-157 has been investigated in preclinical models for potential effects related to angiogenesis and tissue repair processes. TB-500 is modeled after the active region of Thymosin Beta-4 and has been investigated for proposed effects related to cell migration and tissue remodeling. The combination is popular in the research community based on the hypothesis that their proposed mechanisms may be complementary.
| Compound | Dose | Frequency |
|---|---|---|
| BPC-157 | 250–500 mcg | Once or twice daily |
| TB-500 | 2–5 mg | Once or twice weekly |
BPC-157 and TB-500 can be drawn into the same syringe for a combined injection or administered separately. Combining compounds in the same syringe has been described in some research communities but introduces additional variables. Calculate each compound's draw volume separately using the calculator before combining.
Sourcing
Recommended Research Supplier
PSPeptides carries third-party tested, research-grade BPC-157 with published COAs.
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The BPC-157 Protocol Guide
The complete research protocol — subcutaneous vs oral dosing, reconstitution walkthrough, syringe draw reference tables, TB-500 stack guide with mixing instructions, storage, and the most common mistakes.